Publications


TIBS_RQCDetecting and rescuing stalled ribosomes.
Yip MCJ and Shao S. (2021) Trends Biochem. Sci. doi: 10.1018/j.tibs.2021.03.008


STING cyclic dinucleotide sensing originated in bacteria.
Morehouse BR, Govande AA, Millman A, Keszei AFA, Lowey B, Ofir G, Shao S, Sorek R, and Kranzusch PJ. (2020) Nature 586:429-433. PMID 32877915.


CBASS immunity uses CARF-related effectors to sense 3'-5'- and 2'-5'-linked cyclic oligonucleotide signals and protect bacteria from phage infection.
Lowey B, Whiteley AT, Keszei AFA, Morehouse BR, Mathews IT, Antine SP, Cabrera VJ, Kashin D, Niemann P, Jain M, Schwede F, Mekalanos JJ, Shao S, Lee ASY, and Kranzusch PJ. (2020) Cell 182:38-49. PMID 32544385.


TTC5 mediates autoregulation of tubulin via mRNA degradation.
Lin Z, Gasic I, Chandrasekaran V, Peters N, Shao S, Mitchison TJ, and Hegde RS. (2020) Science 367:100-104. PMID 31727855.


Mechanism of ribosome stalling during translation of a poly(A) tail.
Chandrasekaran V*, Juszkiewicz S*, Choi J, Puglisi JD, Brown A, Shao S, Ramakrishnan V, and Hegde RS. (2019) Nat. Struct. Mol. Biol. 26:1132-1140. PMID 31768042.


Activation of GCN2 by the ribosomal P-stalk.
Inglis AJ, Masson GR, Shao S, Perisic O, McLaughlin SH, Hegde RS, and Williams RL. (2019) PNAS 116:4946-4954. PMID 30804176.


The budding yeast nuclear envelope adjacent to the nucleolus serves as a membrane sink during mitotic delay. 
Witkin KL, Chong Y, Shao S, Webster MT, Lahiri S, Walters AD, Lee B, Koh JL, Prinz WA, Andrews BJ, and Cohen-Fix O. (2012) Curr. Biol. 22:1128-1133. PMID 22658600.

 

Tracking F plasmid TraI relaxase processing reactions provides insight into F plasmid transfer. 
Dostál L, Shao S, and Schildbach JF. (2011) Nucleic Acids Res. 39:2658-2670. PMID 21109533.

 

*equal contribution

#co-corresponding author